CAR-T [Tessera Therapeutics](tesseratherapeutics.com) 'Gene writing' Email team and ask if they're looking at chromosomal translocation driven tumors - ewings etc. Massive pediatric market if it can be cracked. Personalised treatment based on specific exon transcript via wgs Theory- able to target only the fusion gene where it exists. Still challenges with TME and access etc but would be potent #### [Strand Therapeutics](strandtx.com) Self replicating miRNA based - tumor specific? / in-vivo car expansion tech Intratumoral Delivery - Self replicating mRNA. Melanoma TNBC and other solid tumors. Payload IL-12 IV Delivery - NSCLC and other solid tumors STX-003 and STX-006